Relative uptake of minoxidil into appendages and stratum corneum and permeation through human skin in vitro

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Relative uptake of minoxidil into appendages and stratum corneum and permeation through human skin in vitro.

We examined uptake of the model therapeutic agent, minoxidil, into appendages, stratum corneum (SC), and through human skin, under the influence of different vehicles. Quantitative estimation of therapeutic drug deposition into all three areas has not previously been reported. Finite doses of minoxidil (2%, w/v) in formulations containing varying amounts of ethanol, propylene glycol (PG), and w...

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ژورنال

عنوان ژورنال: Journal of Pharmaceutical Sciences

سال: 2010

ISSN: 0022-3549

DOI: 10.1002/jps.21856